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KMID : 1011920200210010012
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International Journal of Arrhythmia
2020 Volume.21 No. 1 p.12 ~ p.12
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Accuracy and clinical feasibility of 3D-myocardial thickness map measured by cardiac computed tomogram
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Kwon Oh-Seok
Lee Ji-Su
Lim Se-Hwan
Park Je-Wook
Han Hee-Jin
Yang So-Hyun
Hwang In-Seok
Yu Hee-Tae
Kim Tae-Hoon
Uhm Jae-Sun
Joung Bo-Young
Lee Moon-Hyoung
Pak Hui-Nam
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Abstract
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Background: Although myocardial thickness is an important variable for therapeutic catheter ablation of cardiac arrhythmias, quantification of wall thickness has been overlooked. We developed a software (AMBER) that measures 3D-myocardial thickness using a cardiac computed tomogram (CT) image, verified its accuracy, and tested its clinical feasibility.
Methods: We generated 3D-thickness maps by calculating wall thickness (WT) from the CT images of 120 patients’ hearts and a 3D-phantom model (PhM). The initial vector field of the Laplace equation was oriented to calculate WT with the field lines derived from the 3D mesh. We demonstrate the robustness of the Laplace WT algorithm by comparing with the real thickness of 3D-PhM, echocardiographically measured left ventricular (LV) WT, and regional left atrial (LA) WT reported from previous studies. We conducted a pilot case of catheter ablation for atrial fibrillation (AF) utilizing real-time LAWT map-guided radiofrequency (RF) energy titration.
Results: AMBER 3D-WT had excellent correlations with the real thickness of the PhM (R?=?0.968, p?
Conclusion: We developed and verified an AMBER 3D-cardiac thickness map measured by cardiac CT images for LAWT and LVWT, and tested its feasibility for RF energy titration during clinical catheter ablation.
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KEYWORD
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Myocardial thickness, Computed tomogram, Software
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